Topic: The impact of Aspirin on the reduction of the recurrence of bowel cancer.

Tuesday 15th May

10:30 - 11:15 & 12:00 - 12:45

Article access

If you have not already done so, you will need to register for an OpenAthens account to be able to access the article. There is a link to the registration form on the right. Please contact the Library if you have any problems.

Examining the impact of regular aspirin use and PIK3CA mutations on survival in stage 2 colon cancer, Internal Medicine Journal, 2017 Jan;47(1):88-98.

Discussion points

1. Based on the evidence in this article, what future implications do you think there might be on practice for patients with a diagnosis of colorectal cancer?
2. What potential impact do you think taking aspirin long term may have on patients? (both positive & negative)
3. Do you believe taking aspirin amongst patients with a colorectal diagnosis will become mainstream treatment?
4. What do you feel may be the future implications of this research? 
5. Could aspirin be used as a prophylactic measure for those who have a strong family history of colorectal cancer in their family prior to them receiving a diagnosis?

Further reading

Aspirin & Bowel Cancer - Bowel Cancer UK


Clinical trials
Add Aspirin
This trial is looking at whether aspirin can help stop cancer coming back after treatment in people with early-stage cancer. It is recruiting new people to take part in the trial until the end of September 2021.

CaPP3
This trial is comparing different doses of aspirin, to see the effect on cancer risk in people with Lynch syndrome.

A study looking at whether aspirin and tricagrelar affects how cancer spreads
This study is looking at the effect of aspirin and a drug called ticagrelor on how cancer spreads. It is recruiting people with bowel cancer than has spread to another part of the body until 2 November 2019.

ASPIRE
This trial is looking to see if aspirin helps radiotherapy to work better in people having radiotherapy before surgery for rectal cancer. Recruitment ends on 31 May 2016.

How to Twitter Journal Club...

See our tips for joining #OncJnlClub below.

You can lurk, like, retweet or comment. It's a brilliant experience and a great way to network and share professional knowledge.

1. Follow @OncJnlClub on Twitter. Look out for the next meeting date and article access information.

2. Read the article! It will usually be via a link to OpenAthens (link in menu) on Twitter and on this blog one-two weeks before, with the topics for the chat and further reading. Please contact RSCH Library for assistance.

3. There will be a 10 minute warning before the session starts. Once it begins, introduce yourself - tell the group who you are and what you do.

4. Each chat will last between 45 mins to an hour. The discussion can be fast and difficult to keep up with, so it can be helpful to use a tool to help organise and filter tweets. Tweetchat, Hootsuite or Tweetdeck are very good for making Chats more manageable.

5. Go back and look at your notifications afterwards – it’s easy to miss messages and comments as tweets fly by very quickly.

6. Always use the #OncJnlClub or your tweets won't be seen.

7. See this handy infographic from We Communities for more tips.