Thursday 10 May 2018

Topic: The impact of Aspirin on the reduction of the recurrence of bowel cancer.


Tuesday 15th May

10:30 - 11:15 & 12:00 - 12:45




Article access

If you have not already done so, you will need to register for an OpenAthens account to be able to access the article. There is a link to the registration form on the right. Please contact the Library if you have any problems.

Examining the impact of regular aspirin use and PIK3CA mutations on survival in stage 2 colon cancer, Internal Medicine Journal, 2017 Jan;47(1):88-98.

Discussion points


  1. Based on the evidence in this article, what future implications do you think there might be on practice for patients with a diagnosis of colorectal cancer?
  2. What potential impact do you think taking aspirin long term may have on patients? (both positive & negative)
  3. Do you believe taking aspirin amongst patients with a colorectal diagnosis will become mainstream treatment?
  4. What do you feel may be the future implications of this research? 
  5. Could aspirin be used as a prophylactic measure for those who have a strong family history of colorectal cancer in their family prior to them receiving a diagnosis?
Further reading

Aspirin & Bowel Cancer - Bowel Cancer UK


Clinical trials
Add Aspirin
This trial is looking at whether aspirin can help stop cancer coming back after treatment in people with early-stage cancer. It is recruiting new people to take part in the trial until the end of September 2021.


CaPP3

This trial is comparing different doses of aspirin, to see the effect on cancer risk in people with Lynch syndrome.

A study looking at whether aspirin and tricagrelar affects how cancer spreads
This study is looking at the effect of aspirin and a drug called ticagrelor on how cancer spreads. It is recruiting people with bowel cancer than has spread to another part of the body until 2 November 2019.


ASPIRE
This trial is looking to see if aspirin helps radiotherapy to work better in people having radiotherapy before surgery for rectal cancer. Recruitment ends on 31 May 2016.



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